Lignan Intake May Lower Mortality Risk in Type 2 Diabetes Patients

A new study published in The American Journal of Clinical Nutrition has found that higher lignan intake may reduce the risk of death in individuals with Type 2 Diabetes (T2D), especially among minority ethnic groups. Lignans are natural compounds found in seeds, whole grains, fruits, and vegetables, known for their antioxidant and anti-inflammatory properties.

What Did the Study Find?

Researchers analyzed data from 8,465 individuals with T2D over several decades in two large U.S. studies: the Nurses’ Health Study and the Health Professionals Follow-up Study. The results showed that individuals with higher lignan consumption had a lower risk of death from all causes, including cardiovascular disease (CVD), and cancer.

Key Findings

  • Lower All-Cause Mortality: Patients with the highest lignan intake had a 17% lower risk of death compared to those with the lowest intake.
  • Reduced Cardiovascular Disease (CVD) Mortality: Secoisolariciresinol (SECO), a type of lignan, was linked to a 22% lower risk of CVD-related death.
  • Lower Cancer Mortality: SECO intake was also associated with a 22% lower risk of cancer-related death.
  • Population-Specific Benefits: The protective effects were stronger in non-white individuals, suggesting potential ethnic-specific health benefits.

How Lignans May Benefit Type 2 Diabetes Patients

  • Reduce Inflammation: Chronic inflammation plays a role in diabetes complications, and lignans have anti-inflammatory effects.
  • Improve Heart Health: Lignans may lower cardiovascular risk factors such as high cholesterol and blood pressure.
  • Antioxidant Protection: These compounds help fight oxidative stress, which contributes to cell damage and disease progression.
  • Support Metabolic Health: Some lignans may influence blood sugar regulation, benefiting people with diabetes.

Sources of Lignans

To increase lignan intake, consider adding these lignan-rich foods to your diet:

  • Flaxseeds (one of the richest sources of lignans)
  • Sesame seeds
  • Whole grains (such as rye, oats, and barley)
  • Fruits (like berries, apples, and pears)
  • Vegetables (such as kale, broccoli, and carrots)

For doctors and healthcare professionals, educating patients with Type 2 Diabetes about lignan-rich diets may help improve long-term health outcomes. Encouraging balanced nutrition with seeds, whole grains, fruits, and vegetables could play a role in reducing mortality risks and supporting overall well-being.

Stay informed and guide your patients toward healthier choices!

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